Синдром такоцубо. Клинико-патогенетические аспекты. Основы диагностики и лечения
Аннотация
В обзорной статье представлены современные данные по проблеме синдрома такоцубо; авторами затронуты основные вопросы эпидемиологии, клинической картины, общие патофизиологические механизмы развития заболевания. Рассмотрены вопросы диагностики, основные принципы терапии, а также возможные осложнения и исходы. Представлен диагностический алгоритм, а также обновленные международные диагностические критерии синдрома такоцубо InterTak согласно экспертному документу Европейского общества кардиологов, опубликованному в 2018 году.
Об авторах
И. Н. Суспицына
Краевое ГБУЗ «Алтайский краевой кардиологический диспансер», ФГБОУ ВО «Алтайский государственный медицинский университет» Минздрава РФ
Россия
Россия
Суспицына Ирина Николаевна
Барнаул
И. А. Сукманова
Краевое ГБУЗ «Алтайский краевой кардиологический диспансер», ФГБОУ ВО «Алтайский государственный медицинский университет» Минздрава РФ
Россия
Барнаул
Россия
Барнаул
Список литературы
1. Ghadri J-R, Wittstein IS, Prasad A, Sharkey S, Dote K, Akashi YJ et al. International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology. European Heart Journal. 2018;39(22):2032–46. DOI: 10.1093/eurheartj/ehy076
2. Ghadri J-R, Wittstein IS, Prasad A, Sharkey S, Dote K, Akashi YJ et al. International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management. European Heart Journal. 2018;39(22):2047–62. DOI: 10.1093/eurheartj/ehy077
3. Lüscher TF. Takotsubo syndrome: the Cinderella compared with common acute coronary syndromes. European Heart Journal. 2018;39(22):2017–20. DOI: 10.1093/eurheartj/ehy312
4. Lyon AR, Bossone E, Schneider B, Sechtem U, Citro R, Underwood SR et al. Current state of knowledge on Takotsubo syndrome: a Position Statement from the Taskforce on Takotsubo syndrome of the Heart Failure Association of the European Society of Cardiology: Current state of knowledge on Takotsubo syndrome. European Journal of Heart Failure. 2016;18(1):8–27. DOI: 10.1002/ejhf.424
5. Shilova A.S., Shmotkina A.O., Yafarova A.A., Gilyarov M.Yu. Takotsubo syndrome: Contemporary Views on the Pathogenesis, Prevalence and Prognosis. Rational Pharmacotherapy in Cardiology. 2018;14(4):598–604. [Russian: Шилова А. С., Шмоткина А. О., Яфарова А. А., Гиляров М. Ю. Синдром такоцубо: современные представления о патогенезе, распространенности и прогнозе. Рациональная Фармакотерапия в Кардиологии. 2018;14(4):598-604]. DOI: 10.20996/1819-6446-2018-14-4-598-604
6. Prasad A, Dangas G, Srinivasan M, Yu J, Gersh BJ, Mehran R et al. Incidence and angiographic characteristics of patients with apical ballooning syndrome (takotsubo/stress cardiomyopathy) in the HORIZONS-AMI trial: An analysis from a multicenter, international study of ST-elevation myocardial infarction. Catheterization and Cardiovascular Interventions. 2014;83(3):343–8. DOI: 10.1002/ccd.23441
7. Redfors B, Vedad R, Angerås O, Råmunddal T, Petursson P, Haraldsson I et al. Mortality in takotsubo syndrome is similar to mortality in myocardial infarction — A report from the SWEDEHEART registry. International Journal of Cardiology. 2015;185:282–9. DOI: 10.1016/j.ijcard.2015.03.162
8. Templin C, Ghadri JR, Diekmann J, Napp LC, Bataiosu DR, Jaguszewski M et al. Clinical features and outcomes of Takotsubo (stress) cardiomyopathy. New England Journal of Medicine. 2015;373(10):929–38. DOI: 10.1056/NEJMoa1406761
9. Schneider B, Athanasiadis A, Stöllberger C, Pistner W, Schwab J, Gottwald U et al. Gender differences in the manifestation of tako-tsubo cardiomyopathy. International Journal of Cardiology. 2013;166(3):584–8. DOI: 10.1016/j.ijcard.2011.11.027
10. Roshanzamir S, Showkathali R. Takotsubo Cardiomyopathy A Short Review. Current Cardiology Reviews. 2013;9(3):191–6. DOI: 10.2174/1573403X11309030003
11. Deshmukh A, Kumar G, Pant S, Rihal C, Murugiah K, Mehta JL. Prevalence of Takotsubo cardiomyopathy in the United States. American Heart Journal. 2012;164(1): 66-71. e1. DOI: 10.1016/j.ahj.2012.03.020
12. Aizawa K, Suzuki T. Takotsubo Cardiomyopathy: Japanese perspective. Heart Failure Clinics. 2013;9(2):243–7. DOI: 10.1016/j.hfc.2012.12.001
13. Berton E, Vitali-Serdoz L, Vallon P, Maschio M, Gortani G, Benettoni A. Young girl with apical ballooning heart syndrome. International Journal of Cardiology. 2012; 161(1): e4–6. DOI: 10.1016/j.ijcard.2012.03.012
14. Otillio JK, Harris JK, Tuuri R. A 6-Year-Old Girl with Undiagnosed Hemophagocytic Lymphohistiocytosis and Takotsubo Cardiomyopathy: A Case Report and Review of the Literature. Pediatric Emergency Care. 2014;30(8):561–5. DOI: 10.1097/PEC.0000000000000189
15. Schultz T, Shao Y, Redfors B, Bergmann Sverrisdóttir Y, Råmunddal T, Albertsson P et al. Stress-Induced Cardiomyopathy in Sweden: Evidence for Different Ethnic Predisposition and Altered Cardio-Circulatory Status. Cardiology. 2012;122(3):180–6. DOI: 10.1159/000338814
16. Wittstein IS. Stress Cardiomyopathy: A Syndrome of Catecholamine-Mediated Myocardial Stunning? Cellular and Molecular Neurobiology. 2012;32(5):847–57. DOI: 10.1007/s10571-012-9804-8
17. Parodi G, Citro R, Bellandi B, Provenza G, Marrani M, Bossone E. Revised clinical diagnostic criteria for Tako-tsubo syndrome: The Takotsubo Italian Network proposal. International Journal of Cardiology. 2014;172(1):282–3. DOI: 10.1016/j.ijcard.2013.12.239
18. Madias JE. Why the current diagnostic criteria of Takotsubo syndrome are outmoded: A proposal for new criteria. International Journal of Cardiology. 2014;174(3):468–70. DOI: 10.1016/j.ijcard.2014.04.241
19. Giavarini A, Chedid A, Bobrie G, Plouin P-F, Hagège A, Amar L. Acute catecholamine cardiomyopathy in patients with phaeochromocytoma or functional paraganglioma. Heart. 2013;99(19):1438–44. DOI: 10.1136/heartjnl-2013-304073
20. Finsterer J, Wahbi K. CNS disease triggering Takotsubo stress cardiomyopathy. International Journal of Cardiology. 2014;177(2):322–9. DOI: 10.1016/j.ijcard.2014.08.101
21. Suzuki H, Matsumoto Y, Kaneta T, Sugimura K, Takahashi J, Fukumoto Y et al. Evidence for Brain Activation in Patients with Takotsubo Cardiomyopathy. Circulation Journal. 2014; 78: 256–8. DOI: 10.1253/circj.CJ-13-1276
22. Zhang Z, Jin S, Teng X, Duan X, Chen Y, Wu Y. Hydrogen sulfide attenuates cardiac injury in takotsubo cardiomyopathy by alleviating oxidative stress. Nitric Oxide. 2017; 67:10–25. DOI: 10.1016/j.niox.2017.04.010
23. Ghadri JR, Dougoud S, Maier W, Kaufmann PA, Gaemperli O, Prasad A et al. A PET/CT-follow-up imaging study to differentiate takotsubo cardiomyopathy from acute myocardial infarction. The International Journal of Cardiovascular Imaging. 2014;30(1):207–9. DOI: 10.1007/s10554-013-0311-x
24. Cuisset T, Quilici J, Pankert M, Fourcade L, Poyet R, Lambert M et al. Usefulness of Index of Microcirculatory Resistance to detect microvascular dysfunction as a potential mechanism of stress-induced cardiomyopathy (Takotsubo syndrome). International Journal of Cardiology. 2011;153(3): e51–3. DOI: 10.1016/j.ijcard.2011.02.028
25. Galiuto L, De Caterina AR, Porfidia A, Paraggio L, Barchetta S, Locorotondo G et al. Reversible coronary microvascular dysfunction: a common pathogenetic mechanism in Apical Ballooning or Takotsubo Syndrome. European Heart Journal. 2010;31(11):1319–27. DOI: 10.1093/eurheartj/ehq039
26. Uchida Y, Egami H, Uchida Y, Sakurai T, Kanai M, Shirai S et al. Possible Participation of Endothelial Cell Apoptosis of Coronary Microvessels in the Genesis of Takotsubo Cardiomyopathy. Clinical Cardiology. 2010;33(6):371–7. DOI: 10.1002/clc.20777
27. Blanc C, Zeller M, Cottin Y, Daubail B, Vialatte A-L, Giroud M et al. Takotsubo Cardiomyopathy Following Acute Cerebral Events. European Neurology. 2015;74(3–4):163–8. DOI: 10.1159/000440717
28. Summers MR, Lennon RJ, Prasad A. Pre-Morbid Psychiatric and Cardiovascular Diseases in Apical Ballooning Syndrome (Tako-Tsubo/Stress-Induced Cardiomyopathy)): potential pre-disposing factors? Journal of the American College of Cardiology. 2010;55(7):700–1. DOI: 10.1016/j.jacc.2009.10.031
29. Delmas C, Lairez O, Mulin E, Delmas T, Boudou N, Dumonteil N et al. Anxiodepressive Disorders and Chronic Psychological Stress Are Associated with Tako-Tsubo Cardiomyopathy. Circulation Journal. 2013;77(1):175–80. DOI: 10.1253/circj.CJ-12-0759
30. Sharkey SW, Windenburg DC, Lesser JR, Maron MS, Hauser RG, Lesser JN et al. Natural History and Expansive Clinical Profile of Stress (Tako-Tsubo) Cardiomyopathy. Journal of the American College of Cardiology. 2010;55(4):333–41. DOI: 10.1016/j.jacc.2009.08.057
31. Chan C, Elliott J, Troughton R, Frampton C, Smyth D, Crozier I et al. Acute Myocardial Infarction and Stress Cardiomyopathy following the Christchurch Earthquakes. PLoS ONE. 2013;8(7):e68504. DOI: 10.1371/journal.pone.0068504
32. Lousinha A, Gilkeson R, Bezerra H. Left ventricular outflow tract obstruction and Takotsubo syndrome. Revista Portuguesa de Cardiologia. 2012;31(1):49–51. DOI: 10.1016/j.repc.2011.09.021
33. Kotsiou OS, Douras A, Makris D, Mpaka N, Gourgoulianis KI. Takotsubo cardiomyopathy: A known unknown foe of asthma. Journal of Asthma. 2017;54(8):880–6. DOI: 10.1080/02770903.2016.1276586
34. Gale M, Loarte P, Mirrer B, Mallet T, Salciccioli L, Petrie A et al. Takotsubo Cardiomyopathy in the Setting of Tension Pneumothorax. Case Reports in Critical Care. 2015; 2015: 536931. DOI: 10.1155/2015/536931
35. Y-Hassan S, Settergren M, Henareh L. Sepsis-induced myocardial depression and takotsubo syndrome. Acute Cardiac Care. 2014;16(3):102–9. DOI: 10.3109/17482941.2014.920089
36. Smith SA, Auseon AJ. Chemotherapy-Induced Takotsubo Cardiomyopathy. Heart Failure Clinics. 2013;9(2):233–42. DOI: 10.1016/j.hfc.2012.12.009
37. Citro R, Lyon A, Arbustini E, Bossone E, Piscione F, Templin C et al. Takotsubo Syndrome After Cesarean Section: rare but possible. Journal of the American College of Cardiology. 2018;71(16):1838–9. DOI: 10.1016/j.jacc.2018.02.035
38. Schlossbauer SA, Ghadri J-R, Templin C. Takotsubo-Syndrom – ein häufig verkanntes Krankheitsbild. Praxis. 2016;105(20):1185–92. DOI: 10.1024/1661-8157/a002434
39. Eitel I, von Knobelsdorff-Brenkenhoff F, Bernhardt P, Carbone I, Muellerleile K, Aldrovandi A et al. Clinical Characteristics and Cardiovascular Magnetic Resonance Findings in Stress (Takotsubo) Cardiomyopathy. JAMA. 2011;306(3):277–286. DOI: 10.1001/jama.2011.992
40. Kosuge M, Kimura K. Electrocardiographic findings of takotsubo cardiomyopathy as compared with those of anterior acute myocardial infarction. Journal of Electrocardiology. 2014;47(5):684–9. DOI: 10.1016/j.jelectrocard.2014.03.004
41. Bennett J, Ferdinande B, Kayaert P, Wiyono S, Goetschalkx K, Dubois C et al. Time course of electrocardiographic changes in transient left ventricular ballooning syndrome. International Journal of Cardiology. 2013;169(4):276–80. DOI: 10.1016/j.ijcard.2013.08.126
42. Ghadri JR, Cammann VL, Jurisic S, Seifert B, Napp LC, Diekmann J et al. A novel clinical score (InterTAK Diagnostic Score) to differentiate takotsubo syndrome from acute coronary syndrome: results from the International Takotsubo Registry. European Journal of Heart Failure. 2017;19(8):1036–42. DOI: 10.1002/ejhf.683
43. Nguyen TH, Neil CJ, Sverdlov AL, Mahadavan G, Chirkov YY, Kucia AM et al. N-Terminal Pro-Brain Natriuretic Protein Levels in Takotsubo Cardiomyopathy. The American Journal of Cardiology. 2011;108(9):1316–21. DOI: 10.1016/j.amjcard.2011.06.047
44. Pirzer R, Elmas E, Haghi D, Lippert C, Kralev S, Lang S et al. Platelet and monocyte activity markers and mediators of inflammation in Takotsubo cardiomyopathy. Heart and Vessels. 2012;27(2):186–92. DOI: 10.1007/s00380-011-0132-6
45. Shoukat S, Awad A, Nam DK, Hoskins MH, Samuels O, Higginson J et al. Cardiomyopathy with Inverted Tako-Tsubo Pattern in the Setting of Subarachnoid Hemorrhage: A Series of Four Cases. Neurocritical Care. 2013;18(2):257–60. DOI: 10.1007/s12028-011-9658-9
46. Naderi N, Amin A, Setayesh A, Pouraliakbar H, Mozaffari K, Maleki M. Pheochromocytoma-induced reverse tako-tsubo with rapid recovery of left ventricular function. Cardiology Journal. 2012;19(5):527–31. DOI: 10.5603/cj.2012.0097
47. Burgdorf C, Hunold P, Radke PW, Schunkert H, Kurowski V. Isolated right ventricular stress-induced (“Tako-Tsubo”) cardiomyopathy. Clinical Research in Cardiology. 2011;100(7):617–9. DOI: 10.1007/s00392-011-0293-4
48. Tornvall P, Collste O, Ehrenborg E, Järnbert-Petterson H. A Case-Control Study of Risk Markers and Mortality in Takotsubo Stress Cardiomyopathy. Journal of the American College of Cardiology. 2016;67(16):1931–6. DOI: 10.1016/j.jacc.2016.02.029
49. Stiermaier T, Eitel C, Desch S, Fuernau G, Schuler G, Thiele H et al. Incidence, determinants and prognostic relevance of cardiogenic shock in patients with Takotsubo cardiomyopathy. European Heart Journal: Acute Cardiovascular Care. 2016;5(6):489–96. DOI: 10.1177/2048872615612456
50. Böhm M, Cammann VL, Ghadri JR, Ukena C, Gili S, Di Vece D et al. Interaction of systolic blood pressure and resting heart rate with clinical outcomes in takotsubo syndrome: insights from the International Takotsubo Registry. European Journal of Heart Failure. 2018;20(6):1021–30. DOI: 10.1002/ejhf.1162
51. Citro R, Bossone E, Parodi G, Rigo F, Nardi F, Provenza G et al. Independent Impact of RV Involvement on In-Hospital Outcome of Patients with Takotsubo Syndrome. JACC: Cardiovascular Imaging. 2016;9(7):894–5. DOI: 10.1016/j.jcmg.2015.06.005
52. Sobue Y, Watanabe E, Ichikawa T, Koshikawa M, Yamamoto M, Harada M et al. Physically triggered Takotsubo cardiomyopathy has a higher in-hospital mortality rate. International Journal of Cardiology. 2017; 235:87–93. DOI: 10.1016/j.ijcard.2017.02.090
53. İcli A, Akilli H, Kayrak M, Aribas A, Ozdemir K. Short-term warfarin treatment for apical thrombus in a patient with Takotsubo cardiomyopathy. Cardiovascular Journal of Africa. 2016;27(3): e12–4. DOI: 10.5830/CVJA-2016-011
54. Bharathi K, Kulkarni S, Sadananda K, Gurudatt C. Takotsubo cardiomyopathy precipitated by negative pressure pulmonary oedema following total thyroidectomy. Indian Journal of Anaesthesia. 2016;60(3):202–5. DOI: 10.4103/0019-5049.177872
55. Lu DY, Caplow J, Quatromoni N, Forde-McLean R, Owens AT. Ventricular Septal Defect from Takotsubo Syndrome. Case Reports in Cardiology. 2016; 2016: 2693062. DOI: 10.1155/2016/2693062
56. Citro R, Lyon AR, Meimoun P, Omerovic E, Redfors B, Buck T et al. Standard and Advanced Echocardiography in Takotsubo (Stress) Cardiomyopathy: Clinical and Prognostic Implications. Journal of the American Society of Echocardiography. 2015;28(1):57–74. DOI: 10.1016/j.echo.2014.08.020
Для цитирования:
Суспицына И.Н., Сукманова И.А. Синдром такоцубо. Клинико-патогенетические аспекты. Основы диагностики и лечения. Кардиология. 2020;60(2):96-103. https://doi.org/10.18087/cardio.2020.2.n521
For citation:
Suspitsyna I.N., Sukmanova I.A. Takotsubo syndrome. Clinical and pathogenetic aspects. Basics of diagnosis and treatment. Kardiologiia. 2020;60(2):96-103. https://doi.org/10.18087/cardio.2020.2.n521
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