Хроническая обструктивная болезнь легких и сердечно-сосудистая коморбидность
Аннотация
В последние годы пришло большее понимание гетерогенности и сложности хронической обструктивной болезни легких (ХОБЛ) с точки зрения интегральной клинической оценки тяжести, патофизиологии и взаимосвязи с другой патологией. Типичный пациент ХОБЛ страдает в среднем 4 и более сопутствующими заболеваниями и каждый день примерно треть пациентов принимают от 5 до 10 различных препаратов. Механизмы взаимовлияния ХОБЛ и сердечно-сосудистых заболеваний (ССЗ) включают влияние системного воспаления, гипервоздушности (гиперинфляции) легких и бронхиальной обструкции. Риск развития CCЗ у пациентов с ХОБЛ в среднем в 2–3 раза выше, чем у лиц сопоставимого возраста в общей популяции даже с учетом риска табакокурения. Распространенность ишемической болезни сердца, сердечной недостаточности и нарушений ритма среди больных ХОБЛ значительно выше, чем в общей популяции. В статье подробно обсуждается безопасность назначения различных групп препаратов для терапии ССЗ у пациентов с ХОБЛ. Достичь успеха в понимании и ведении пациентов с ХОБЛ и ССЗ возможно при использовании интегрального мультидисциплинарного подхода.
Об авторах
З. Р. Айсанов
ФГБОУ ВО «РНИМУ им. Н. И. Пирогова» МЗ РФ
Россия
Россия
117997, Москва, ул. Островитянова, д. 1
А. Г. Чучалин
ФГБОУ ВО «РНИМУ им. Н. И. Пирогова» МЗ РФ
Россия
Россия
117997, Москва, ул. Островитянова, д. 1
Е. Н. Калманова
ФГБОУ ВО «РНИМУ им. Н. И. Пирогова» МЗ РФ
Россия
Россия
117997, Москва, ул. Островитянова, д. 1
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Рецензия
Для цитирования:
Айсанов З.Р., Чучалин А.Г., Калманова Е.Н. Хроническая обструктивная болезнь легких и сердечно-сосудистая коморбидность. Кардиология. 2019;59(8S):24-36. https://doi.org/10.18087/cardio.2572
For citation:
Aisanov Z.R., Chuchalin A.G., Kalmanova E.N. Chronic obstructive pulmonary disease and cardiovascular comorbidity. Kardiologiia. 2019;59(8S):24-36. (In Russ.) https://doi.org/10.18087/cardio.2572
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