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Проблема безопасности липидснижающей терапии

https://doi.org/10.18087/cardio.2505

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Аннотация

Настоящая работа посвящена анализу современных публикаций, оценивающих безопасность липидснижающей терапии. Поиск литературы был проведен на сайтах кардиологических обществ, а также по онлайновым базам данных PubMed, EMBASE, eLibrary с использованием ключевых слов: статины, непереносимость статинов, липидснижающая терапия, статины и безопасность, statins, statin intolerance, lipid lowering therapy, statin safety, statin аdverse effects. Основное внимание уделено именно статинам, так как они считаются самыми назначаемыми, высокоэффективными и безопасными препаратами при первичной и  вторичной кардиоваскулярной профилактике. В  данном литературном обзоре последовательно изложена информация о миопатиях, печеночной и почечной дисфункции, потенцировании СД, а также о ряде других возможных неблагоприятных эффектов липидснижающей терапии. Автором сделан вывод, что несмотря на высокую безопасность статинов, признанную всеми кардиологическими сообществами мира, практикующие врачи все же продолжают необоснованно отменять статины, подвергая больного еще большей опасности.

Об авторе

М. B. Зыков
ФГБНУ «НИИ КПССЗ»
Россия


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Для цитирования:


Зыков М.B. Проблема безопасности липидснижающей терапии. Кардиология. 2019;59(5S):13-26. https://doi.org/10.18087/cardio.2505

For citation:


Zykov M.V. The problem of safety of lipid-lowering therapy. Kardiologiia. 2019;59(5S):13-26. (In Russ.) https://doi.org/10.18087/cardio.2505

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