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Кардиология

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Участие микроРНК в развитии ишемической болезни сердца

https://doi.org/10.18087/cardio.2019.10.n558

Полный текст:

Аннотация

Атерогенез - сложный процесс, в котором участвуют разные типы клеток и регуляторных молекул. Открытые в конце ХХ века молекулы микроРНК служат важными регуляторами ряда патофизиологических процессов, вовлеченных в атерогенез. В обзоре рассматриваются данные об участии различных микроРНК в развитии атеросклероза и его основных клинических проявлений и обсуждается возможность использования микроРНК в качестве диагностических маркеров этих заболеваний.

Об авторах

Н. Г. Кукава
Институт клинической кардиологии им. А.Л. Мясникова, ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России
Россия

Нино Гуриеловна Кукава - кардиолог отдела неотожной кардиологии НМИЦ кардиологии; к.м.н.

Москва



Р. М. Шахнович
Институт клинической кардиологии им. А.Л. Мясникова, ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России; ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России
Россия

Роман Михайлович Шахнович – доктор медицинских наук, профессор, ведущий научный сотрудник отдела неотложной кардиологии НМИЦ кардиологии

Москва



Г. Ж. Осьмак
Институт экспериментальной кардиологии, ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России
Россия

Герман Жакович Осьмак

Москва



Н. М. Баулина
Институт экспериментальной кардиологии, ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России
Россия

Наталья Михайловна Баулина

Москва



Н. А. Матвеева
Институт экспериментальной кардиологии, ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России
Россия

Наталья Алексеевна Матвеева

Москва



О. О. Фаворова
Институт экспериментальной кардиологии, ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России
Россия

Ольга Олеговна Фаворова - профессор, доктор биологических наук.

Москва



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Для цитирования:


Кукава Н.Г., Шахнович Р.М., Осьмак Г.Ж., Баулина Н.М., Матвеева Н.А., Фаворова О.О. Участие микроРНК в развитии ишемической болезни сердца. Кардиология. 2019;59(10):78-87. https://doi.org/10.18087/cardio.2019.10.n558

For citation:


Kukava N.G., Shkhnovich R.M., Osmak G.Z., Baulina N.M., Matveeva N.A., Favorova O.O. The Role of microRNA in the Development of Ischemic Heart Disease. Kardiologiia. 2019;59(10):78-87. (In Russ.) https://doi.org/10.18087/cardio.2019.10.n558

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