Нефрологические аспекты применения ривароксабана и других прямых пероральных антикоагулянтов при фибрилляции предсердий неклапанной этиологии
https://doi.org/10.18087/cardio.2019.6.n516
Аннотация
Хроническая болезнь почек (ХБП) – мощный фактор риска развития сердечно-сосудистых заболеваний (ССЗ), который сопровождается повышением риска госпитализаций по поводу обострения хронической сердечной недостаточности (ХСН), неблагоприятных исходов при инфаркте миокарда, смерти от ССЗ и их осложнений. Среди неблагоприятных исходов следует отметить повышение риска развития фибрилляции предсердий (ФП). В статье рассматриваются современные подходы к терапии ФП у больных с ХБП разных стадий, приводятся данные о преимущества тех или иных прямых пероральных антикоагулянтов (ППОАК), а также сравнительные особенности терапии ППОАК и варфарином. Рассматриваются особенности фармакокинетики и фармакодинамики ППОАК, которые определяют особенности терапии при ХБП.
Об авторе
М. М. БатюшинРоссия
Батюшин Михайлович Михаил – кафедра внутренних болезней № 2 (профессор), нефрологическое отделение (заведующий)
Ростов-на-Дону
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Рецензия
Для цитирования:
Батюшин М.М. Нефрологические аспекты применения ривароксабана и других прямых пероральных антикоагулянтов при фибрилляции предсердий неклапанной этиологии. Кардиология. 2019;59(6):60-69. https://doi.org/10.18087/cardio.2019.6.n516
For citation:
Batiushin M.M. The Nephrological Aspects of the Use of Rivaroxaban and Other Direct Peroral Anticoagulants in Non-Valvular Atrial Fibrillation. Kardiologiia. 2019;59(6):60-69. (In Russ.) https://doi.org/10.18087/cardio.2019.6.n516