Фибрилляция предсердий и когнитивные нарушения: особенности взаимосвязи, механизмов развития и профилактики

В статье обсуждаются вопросы развития когнитивного дефицита у пациентов с фибрилляцией предсердий (ФП), приводятся данные о механизмах развития когнитивных нарушений на фоне ФП. Обсуждается вопрос о возможном снижении риска когнитивных нарушений на фоне антикоагулянтной терапии с целью профилактики инсульта при ФП и о том, что разные антикоагулянты обладают различными свойствами, которые могут иметь значение для пациентов. Так, пациенты с когнитивными нарушениями чаще забывают принимать препарат, что может повлечь за собой серьезные, возможно, смертельные последствия. В связи с этим удобство приема препарата может иметь ключевое значение. Препарат ривароксабан, имеющий однократный режим дозирования и календарную упаковку, может позволить пациенту лучше соблюдать рекомендации врача. Таким образом, ривароксабан может помочь соблюдению высокой приверженности к лечению, которая служит главным условием обеспечения комплексной защиты пожилого пациента с ФП, в которой он нуждается, включая также: защиту от инсульта при высоких показателях безопасности, снижение риска развития коронарных осложнений и ухудшения функции почек.

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