Синдром старческой астении как независимый предиктор неблагоприятного прогноза для пациентов с хронической сердечной недостаточностью
Аннотация
В обзоре представлены результаты клинических исследований, посвященных изучению синдрома старческой астении («хрупкости») и хронической сердечной недостаточности (ХСН). Освещены последние данные по распространенности «хрупкости» у пациентов с ХСН. Представлены особенности патофизиологических путей, лежащих в основе развития как синдрома старческой астении, так и ХСН; проанализирована роль «хрупкости» в прогрессировании и осложненном течении ХСН. Синдром старческой астении на фоне ХСН рассматривается как независимый предиктор неблагоприятного прогноза и высокой смертности в данной когорте пациентов. Сделан вывод о необходимости включения в клиническую практику методов оценки «хрупкости» у пациентов с ХСН с последующей стратификацией риска и выбором индивидуальной тактики ведения.
Ключевые слова
Об авторах
К. Е. Кривошапова
ФГБНУ «НИИ комплексных проблем сердечно-сосудистых заболеваний»; ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России
Россия
Россия
научный сотрудник лаборатории коморбидности при сердечно-сосудистых заболеваниях, к. м. н.
Кемерово
Е. А. Вегнер
ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России
Россия
Россия
аспирант кафедры кардиологии и сердечно-сосудистой хирургии
Кемерово
О. Л. Барбараш
ФГБНУ «НИИ комплексных проблем сердечно-сосудистых заболеваний»; ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России
Россия
Россия
Директор института; заведующая кафедрой кардиологии и сердечно-сосудистой хирургии, д. м. н., профессор, член-корреспондент РАН
Кемерово
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Рецензия
При поддержке: Работа выполнена при поддержке комплексной программы фундаментальных научных исследований СО РАН в рамках фундаментальной темы ФГБНУ «НИИ КПССЗ» № 0546‑2019‑0003 «Мультифокальный атеросклероз и коморбидные состояния. Особенности диагностики, управления рисками в условиях крупного промышленного региона Сибири». Конфликт интересов не заявлен.
Для цитирования:
Кривошапова К.Е., Вегнер Е.А., Барбараш О.Л. Синдром старческой астении как независимый предиктор неблагоприятного прогноза для пациентов с хронической сердечной недостаточностью. Кардиология. 2022;62(3):89-96. https://doi.org/10.18087/cardio.2022.3.n1206
For citation:
Krivoshapova K.E., Vegner E.A., Barbarash O.L. Frailty syndrome as an independent predictor of adverse prognosis in patients with chronic heart failure. Kardiologiia. 2022;62(3):89-96. (In Russ.) https://doi.org/10.18087/cardio.2022.3.n1206
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