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Доказательные факты, которые могли повлиять на тактику лечения больных артериальной гипертонией в период после опубликования результатов исследования SPRINT

https://doi.org/10.18087/cardio.2020.8.n1177

Полный текст:

Аннотация

Статья посвящена обсуждению результатов вторичных анализов данных, полученных в исследовании SPRINT, которые были опубликованы в последние годы. Обсуждаются нерешенные вопросы тактики лечения пациентов с артериальной гипертонией, в частности проблемы выбора оптимального уровня артериального давления (АД) в подгруппе пациентов с определенными характеристиками, включая пациентов пожилого и старческого возраста, пациентов с хронической болезнью почек, а также пациентов с артериальной гипертонией, которые продолжают курить. Обсуждаются проблемы порогового рассчитанного риска развития осложнений сердечно-сосудистых заболеваний, при котором достигаются наибольшие преимущества при использовании более интенсивных режимов антигипертензивной терапии. Кроме того, в статье рассматривается вопрос о подходах к выбору антигипертензивных препаратов в современных условиях. Обсуждается роль кандесартана в лечении артериальной гипертонии как сартана, наиболее изученного у широкого круга пациентов. Рассматривается проблема быстрого выраженного повышения АД в отсутствие поражений органов-мишеней, приводятся данные о роли каптоприла в такой клинической ситуации.

Об авторах

С. Р. Гиляревский
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Москва
Россия
Доктор медицинских наук, профессор кафедры клинической фармакологии и терапии РМАНПО


Н. Г. Бенделиани
Институт коронарной и сосудистой хирургии (ИКиСХ), консультативно-диагностический центр, НМИЦССХ им. А.Н.Бакулева, Москва
Россия

Доктор медицинских наук, старший научный сотрудник научно-консультативного отделения института коронарной и сосудистой хирургии (ИКиСХ) консультативно-диагностического центра (КДЦ) 



М. В. Голшмид
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Москва
Россия

Кандидат медицинских наук, доцент кафедры клинической фармакологии и терапии РМАНПО



Г. Ю. Захарова
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Москва
Россия

 

К.м.н., доцент кафедры клинической фармакологии и терапии ФГБОУ ДПО РМАНПО



И. М. Кузьмина
НИИ скорой помощи имени Н.В. Склифосовского Департамента здравоохранения г. Москвы, Москва
Россия

Кандидат медицинских наук, заведующий научным отделением неотложной кардиологии ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»



И. И. Синицина
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Москва
Россия
Д.м.н., профессор кафедры клинической фармакологии и терапии ФГБОУ ДПО РМАНПО


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Для цитирования:


Гиляревский С.Р., Бенделиани Н.Г., Голшмид М.В., Захарова Г.Ю., Кузьмина И.М., Синицина И.И. Доказательные факты, которые могли повлиять на тактику лечения больных артериальной гипертонией в период после опубликования результатов исследования SPRINT. Кардиология. 2020;60(8):130-140. https://doi.org/10.18087/cardio.2020.8.n1177

For citation:


Gilyarevsky S.R., Bendeliani N.G., Golshmid M.V., Zaharova G.Yu., Kuzmina I.M., Sinitcina I.I. Evidence-Based Information Which Could Influence Arterial Hypertension Treatment Approach after Publication of SPRINT Trial Results. Kardiologiia. 2020;60(8):130-140. (In Russ.) https://doi.org/10.18087/cardio.2020.8.n1177

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