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Обзор посвящен применению антиагрегантов. Рассматриваются патогенез артериального тромбоза, механизмы действия антиагрегантов и рекомендации по применению препаратов этого класса для первичной профилактики сердечно-сосудистых заболеваний и предупреждения атеротромботических осложнений стабильной ишемической болезни сердца. Приводятся сведения о механизмах развития и причинах резистентности к антиагрегантам. Обсуждаются проблема безопасности антиагрегантной терапии, способы снижения риска кровотечений и предотвращения гастропатии, индуцированной ацетилсалициловой кислотой.

Об авторах

Н. Б. Перепеч
ФГБОУВО «Санкт-Петербургский государственный университет»

И. Е. Михайлова
ФГБОУВО «Санкт-Петербургский государственный университет»

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