2018


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2018/№2

Антиагреганты в первичной профилактике сердечно- сосудистых заболеваний и профилактике атеротромбоза у больных со стабильной формой ишемической болезни сердца: аспекты эффективности и безопасности

Перепеч Н. Б., Михайлова И. Е.
ФГБОУ ВО «Санкт-Петербургский государственный университет», Санкт-Петербург

Ключевые слова: атеротромбоз, антиагреганты, ацетилсалициловая кислота, кровотечения, гастропатия

DOI: 10.18087/cardio.2018.2.10035

Обзор посвящен применению антиагрегантов. Рассматриваются патогенез артериального тромбоза, механизмы действия антиагрегантов и рекомендации по применению препаратов этого класса для первичной профилактики сердечно-сосудистых заболеваний и предупреждения атеротромботических осложнений стабильной ишемической болезни сердца. Приводятся сведения о механизмах развития и причинах резистентности к антиагрегантам. Обсуждаются проблема безопасности антиагрегантной терапии, способы снижения риска кровотечений и предотвращения гастропатии, индуцированной ацетилсалициловой кислотой.
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Перепеч Н. Б., Михайлова И. Е. Антиагреганты в первичной профилактике сердечно-сосудистых заболеваний и профилактике атеротромбоза у больных со стабильной формой ишемической болезни сердца: аспекты эффективности и безопасности. Кардиология. 2018;58(2):55–67.

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